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PSOregon Intensive Serum 50ml
PSOregon Intensive Serum 50ml
PSOregon Intensive Serum 50ml

PSOregon Intensive Serum 50ml

In Stock
£12.45

PSOregon Intensive Rescue Serum is a fast-acting, targeted treatment designed to calm, soften and restore comfort to smaller, hard-to-heal patches of psoriasis-prone skin. Lightweight and non-greasy, it helps reduce visible scaling, soothe soreness and relieve irritation in areas where skin feels most uncomfortable.

Formulated with concentrated Oregon Grape Root extract, alongside caffeine and carefully selected botanical actives, the serum helps regulate excessive skin cell turnover, soften rough plaques and support the skin’s natural recovery process. Ideal for stubborn or persistent flare-up areas, it can be applied directly where more intensive support is needed.

 Target and Soothe 
 Psoriasis Patches 

PSOregon Intensive Serum is a naturally active rescue solution designed to soothe and restore sore, red, and scaly patches of psoriasis-prone skin.

With clinically proven Oregon Grape Root and fast-acting caffeine, it reduces scale build-up, calms redness, and softens irritated areas.

Perfect for smaller, hard-to-heal patches, it promotes smoother, healthier skin with gentle, effective care.

AS SEEN ON

KALME as seen on press coverageKALME as seen on press coverage

 What to Expect 
 Our Promise 

We understand that many people with psoriasis have tried products and treatments that didn’t live up to their promises.

At PSOregon, we believe in honesty and setting clear, realistic expectations from the start.

Our Intensive Serum is designed to work with your skin over time, addressing the root causes of psoriasis.

Using targeted, naturally active ingredients, it tackles the fundamental symptoms of scaly skin by inhibiting excessive skin cell turnover while repairing, hydrating, and softening dry, scaly plaques.

Long-lasting results don’t happen overnight, but this journey will lead to healthier, softer skin.

Knowing what to expect along the way can help you feel confident that real improvements are happening.

Week 1:

Skin feels calmer and less reactive, with noticeable reductions in itching and irritation.

Patches of red, scaly skin start to feel softer, and flaking decreases.

Weeks 2–3:

Redness and sensitivity reduce further, and scaly plaques begin to break up.

Patches become less raised and start transforming from dry and silvery to softer, smoother, and pinker.

Weeks 4–5:

Plaques continue to diminish in size and smooth out, with fewer new patches forming.

The skin appears healthier overall, and discomfort is significantly reduced.

After 1 Month:

Skin looks clearer and healthier, with softer, pale pink plaques that are noticeably smaller and less dry.

Consistent use shows visible progress in remission and improved texture.

Long-Term:

Regular application helps keep plaques smaller, less severe, and less reactive.

New flare-ups are minimised, leaving skin calmer, smoother, and more comfortable, so you can feel confident in your appearance.

 The Complete 
 Oregon Routine 

Skin specialists often say that consistency is the key to managing psoriasis-prone skin and scalps.

Trying different products on scaly, hypersensitive skin can feel like a game of Russian roulette—and it usually leads to more discomfort.

So, why risk it...

That’s why we’ve created four core products designed specifically for skin like yours!

Our PSOregon Skin Repair Routine works to improve the underlying condition of your skin, reducing the need for other products that might disrupt your skin’s recovery.

All we ask from you is a commitment to stick with us and experience the proven benefits our system can offer your skin.

 MAINTENANCE CREAM 

Reduces & softens
plaque build-up
in larger areas

KALME Skin CleansingKALME Skin Cleansing

 INTENSIVE SERUM 

SOS for areas of
very sore hard
to heal skin

KALME Undercoat Shield & De-SensitiseKALME Undercoat Shield & De-Sensitise

 SHAMPOO 

Reduces itching,
flaking & scalp
scale build-up

KALME Chameleon concealerKALME Chameleon concealer

 CONDITIONER 

Softens scalp scales,
supports hair growth
& conditions hair

 Our Routine 
 Step by Step 

KALME MORNING ROUTINEKALME MORNING ROUTINE

Maintenance Cream:

Apply PSOregon Maintenance Cream to larger areas of affected skin in the morning and evening, immediately after bathing. It softens and hydrates, providing relief for dry, scaly skin.

Intensive Serum:

Apply PSOregon Intensive Serum to smaller, sore, or hard-to-heal areas in the morning and evening for targeted relief.

KALME Evening RoutineKALME Evening Routine

Shampoo & Conditioner:

Wash your hair with PSOregon Shampoo & Conditioner.

Wrap wet hair in a warm towel for 10–15 minutes to allow the products to penetrate deeply. Whenever possible, avoid blow-drying, as air-drying is gentler on sensitive scalps.

KALME Evening RoutineKALME Evening Routine

Clothing Tips:

Avoid wearing synthetic or tight clothing on affected areas. Choose cotton undergarments to allow your skin to breathe.

Wear cotton pyjamas or sleepwear after applying products to allow your skin to breathe overnight and prevent irritation.

 Special 
 Offers 

Aqua, Glyceryl Polyacrylate, Berberis Aquifolium (Oregon Grape) Extract, Glycerine, Helianthus Annu (Sunflower) Oil, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Mannitol, Ammonium Glcyrrhizate ( liquorice extract), Caffeine, Zinc Gluconate, Aesculus Hippocastanum (Horse Chestnut) Extract, Formic Acid, Iodpropynyl Butylcarbamate, Polyaminopropyl Biguanide, Potassium Sorbate, Sodium Benzoate, Sorbitol, 2-Bromo-2-Nitropropane-1, 3-Dio

PSOregon Intensive Serum

PSOregon Intensive Rescue Serum is a fast-acting, targeted treatment developed for smaller, stubborn patches of sore, red and scaly skin that take longer to settle and improve. It is designed to be used where skin needs extra care and more intensive support.

The serum contains higher concentrations of active ingredients, including clinically studied Oregon Grape Root, shown to help reduce scale build-up, soften rough skin and calm underlying irritation associated with psoriasis-prone skin.

Enriched with caffeine, the formula helps the active ingredients work more quickly, supporting faster soothing and comfort where skin feels most uncomfortable.

PSOregon Intensive Serum 50ml

Improves the skin's appearance

This intensive serum is most effective when used daily as part of a regular maintenance and preventative skincare routine for psoriasis-prone skin. It can be applied as often as needed and is suitable for use on the body or face.

Ideal for smaller, hard-to-heal areas, the serum can also be used during periods when skin requires more intensive repair and targeted care.

Like all PSOregon products, the formula is made using carefully selected natural ingredients, has a mild, herbal scent, and is free from coal tar.

 

PSOregon Intensive Serum 50ml

What is Oregon Grape Root?

Oregon Grape Root (OGR) is a plant native to North America that has been extensively studied for its benefits in psoriasis-prone skin. Research has shown that compounds found in Oregon Grape Root extracts help regulate biological processes involved in excessive skin cell production.

Published studies indicate that OGR exhibits inhibitory activity against lipoxygenase, an enzyme associated with inflammatory pathways and accelerated skin cell turnover in psoriasis. At a cellular level, Oregon Grape Root has also been shown to help moderate keratinocyte activity, supporting healthier skin renewal and reducing visible scaling and redness.

This unique mechanism makes Oregon Grape Root particularly well-suited for ongoing use in skincare products designed to calm irritation, soften rough skin and support long-term skin balance.

Free from

PSOregon products contain no animal-derived ingredients and are free from harsh or irritating chemicals, including Sodium Lauryl Sulphate (SLS), MI, parabens and added perfumes. They also contain no coal tar or mineral oil.

PSOregon products can be used between psoriasis flare-ups as part of a preventative skincare routine, helping to reduce the frequency and intensity of future flare-ups while maintaining skin comfort and resilience.

PSOregon Intensive Serum 50ml